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Index > Protein center > Dvl1(Gene name) > Rat
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  • Dvl1 (Gene name),
  • Segment polarity protein dishevelled homolog DVL-1 (Protein name ),  DVL1_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Dvl1;
    Protein name:
    Segment polarity protein dishevelled homolog DVL-1(Dishevelled-1);
    Alternative:
    DSH homolog 1;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Interacts with BRD7 and INVS. Interacts through its PDZ domain with the C-terminal regions of VANGL1, VANGL2 and CCDC88C/DAPLE. Interacts (via PDZ domain) with NXN. Interacts with CXXC4. Interacts with ARRB1; the interaction is enhanced by phosphorylation of DVL1. Interacts with CYLD. Interacts (via PDZ domain) with RYK. Self-associates (via DIX domain) and forms higher homooligomers. Interacts (via PDZ domain) with DACT1 and FZD7, where DACT1 and FZD7 compete for the same binding site.
    Function:
    Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes. Required for LEF1 activation upon WNT1 and WNT3A signaling.
    Subcellular Location:
    Cell membrane Peripheral membrane protein Cytoplasmic side Cytoplasm cytosol Cytoplasmic vesicle Localizes at the cell membrane upon interaction with frizzled family members.
    Protein Attributes:
    Sequence length:
    695
    Sequence:
    50:
    MAETKIIYHM | DEEETPYLVK | LPVAPERVTL | ADFKNVLSNR | PVHAYKFFFK | 
    100:
    SMDQDFGVVK | EEIFDDNAKL | PCFNGRVVSW | LVLAEGAHSD | AGSQGTDSHT | 
    150:
    DLPPPLERTG | GIGDSRPPSF | HPNVASSRDG | MDNETGTESM | VSHRRERARR | 
    200:
    RNRDEAARTN | GHPRGDRRRE | LGLPPDSAST | VLSSELESSS | FIDSDEEDNT | 
    250:
    SRLSSSTEQS | TSSRLIRKHK | CRRRKQRLRQ | TDRASSFSSI | TDSTMSLNII | 
    300:
    TVTLNMERHH | FLGISIVGQS | NDRGDGGIYI | GSIMKGGAVA | ADGRIEPGDM | 
    350:
    LLQVNDVNFE | NMSNDDAVRV | LREIVSQTGP | ISLTVAKCWD | PTPRSYFTIP | 
    400:
    RADPVRPIDP | AAWLSHTAAL | TGALPRYGTS | PCSSAITRTS | SSSLTSSVPG | 
    450:
    APQLEEAPLT | VKSDMSAIVR | VMQLPDSGLE | IRDRMWLKIT | IANAVIGADV | 
    500:
    VDWLYTHVEG | FKERREARKY | ASSMLKHGFL | RHTVNKITFS | EQCYYVFGDL | 
    550:
    CSNLASLNLN | SGSSGASDQD | TLAPLPHPSV | PWPLGQGYPY | QYPGPPPCFP | 
    600:
    PAYQDPGFSY | GSGSAGSQQS | EGSKSSGSTR | SSHRTPGREE | RRATGAGGSG | 
    650:
    SESDHTVPSG | SGSTGWWERP | VSQLSRGSSP | RSQASAVAPG | LPPLHPLTKA | 
    695:
    YAVVGGPPGG | PPVRELAAVP | PELTGSRQSF | QKAMGNPCEF | FVDIM
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    KEGG:
    Pfam:
    String:
    UniGene:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Dishevelled-1
    Cat.:
    E15104h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Rat Dishevelled-1
    MSDS:
    Please sign in first.
    ELISA Kit for Rat Dishevelled-1
    MSDS:
    Please sign in first.
    CLIA Kit for Rat Dishevelled-1
    MSDS:
    Please sign in first.
    CLIA Kit for Rat Dishevelled-1
    MSDS:
    Please sign in first.
    CLIA Kit for Rat Dishevelled-1
    Cat.:
    U15104h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Rat Dishevelled-1
    Polyclonal Antibody for Rat Dishevelled-1
    Polyclonal Antibody for Rat Dishevelled-1
    Monoclonal Antibody for Rat Dishevelled-1
    Monoclonal Antibody for Rat Dishevelled-1
    Monoclonal Antibody for Rat Dishevelled-1
    Protein for Rat Dishevelled-1
    Protein for Rat Dishevelled-1
    Protein for Rat Dishevelled-1

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Mapping and sequencing rat dishevelled-1: a candidate gene for cerebral ischaemic insult in a rat model of stroke."
      de Lange R.P.J. , Burr K. , Clark J.S. , Negrin C.D. , Brosnan M.J. , St Clair D.M. , Dominiczak A.F. , Shaw D.J.
      Neurogenetics3:99-106(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA]
      strain: Wistar Kyoto.
    2. 2.
      "Inhibition of the Wnt signaling pathway by Idax, a novel Dvl-binding protein."
      Hino S. , Kishida S. , Michiue T. , Fukui A. , Sakamoto I. , Takada S. , Asashima M. , Kikuchi A.
      Mol. Cell. Biol.21:330-342(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH CXXC4
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